Faculty Profile
blog.pmean.com
Research Description
I am interested in research about the research process. One application is the use of Bayesian Statistics to monitor the patient accrual process during a prospective clinical trial. Many trials fall behind in patient accrual, leading to major delays in completing the research and/or serious shortfalls in proposed sample size. The Bayesian model helps researchers predict trial completion more accurately by forcing them to describe their prior beliefs about the patient accrual process. The model also allows a researcher to monitor patient accrual during the trial, allowing early adjustments to the research if patient accrual is much slower than expected.
I'm also interested in auditing the existing research record to look for general trends and patterns in how research is conducted and reported. How often, for example, do research reports still rely on methodologies like post hoc power calculations that have been discredited in the research community? How often does IRB approved research fail to follow the proposed research protocol and how often is the research left unpublished?
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