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Bacterial Cell Wall Metabolomics

    PROFESSOR - William Gutheil

    Contact Detail
    William Gutheil


    We are examining the cell wall biosynthesis pathway is several bacterial strains, in particular to examine the response of cell wall intermediate levels to antibiotic exposure in antibiotic sensitive and resistant strains. Cell are collected, lysed, and UDP-linked and amino acid intermediated quantified by HPLC-MS.

    Health Sciences Building, room 4240, 2464 Charlotte.

    Basic laboratory skills.

    Project Timeline

    Logistics and Compensation
    At present no stipend is available, but this may change if funding permits. The School of Pharmacy does not have a course credit mechanism, but a students home department may have a mechanism that the student can use.

    Primarily to help graduate students grow, treat, and collect bacterial samples. Prepare bacterial extracts for analysis. Perform amino acid derivatization reaction. Prepare samples for HPLC-MS analysis. Run LC-MS analyses, and collect and summarize results from these experiments.

    Project-related Tags
    Analytical  Antibiotic  Bacterial  Cell Wall  Chemistry  LC-MS  Metabolomics.  Resistance  

    Last Updated
    Sep 27, 2017

Now that UR-Linked has helped you to identify a faculty project that interests you and for which you might be qualified, be sure to review the essential steps in contacting a potential faculty mentor.

The Director of Undergraduate Research, Dr. Jane Greer., can provide you with further guidance about finding and connecting with faculty mentors at UMKC.

Once you have reviewed the essential steps to prepare for connecting with a potential faculty mentor, you can use the "Contact Details" for this project to connect with the faculty member and to begin a conversation about how you might get involved.